General references General references Leong A S-Y, Cooper K and Leong FJ W-M. Manual of diagnostic antibodies for immunohistology.

Diagnostic Immunohistochemistry presents the latest information and most reliable guidance on immunohistological diagnoses in surgical pathology. Newsleecher 5 Beta 6 Rapidshare Movies. Dabbs, MD and other leading experts bring you state-of-the-art coverage on genomic and theranostic applications, molecular anatomic pathology, immunocytology, Non-Hodgkin’s lymphoma, and more.

First edition published 1998, Oxford University Press, ISBN 1 900 151 316. Second edition published 2003, Greenwich Medical Media ISBN 1 84110 100 1.

This is an excellent manual. The core of the book consists of sections devoted to each antigen/antibody, in alphabetical order. It gives some technical information as well as immunoreactivities and diagnostic usage. The book concludes with tables of differential diagnoses and the discriminating antibodies. The text of the first edition is highly conserved in the second. In addition, the entries for each antibody have been expanded by a median of 12% (range 0-30%).

There are also 30 new antibodies, not listed in the first edition, increasing the number listed by 17% to 180. This includes a couple of very important additions, namely CD117 and TTF-1. The combination of new entries and expanded entries gives an overall increase in the length of the text of about 30%. The number of tables in the appendices has also increased by 30%, bringing the total to 52. These tables list the antibodies which are informative in particular situations and differentials. A minor niggle, but there are some perversities in the ordering of antibodies, which, erratically, have been put in strictly alphabetical order, with CD103 falling between CD10 and CD11, cytokeratin 20 preceding cytokeratin 7. Yet CD117 is after CD99 and CDw75 is correctly positioned between CD74 and CD79a.

An impressive number of the references are from 2002. Diagnostic Immunohistochemistry edited by Professor D. Dabbs, Churchill Livingstone. ISBN 0 443 06566 7. Published 2001. This is the most substantial publication to date dedicated to immunohistochemistry.

It is organised by organ-system. Each chapter is designed to be stand-alone, which has perhaps expedited publication, but has resulted in significant duplication. In defense of this, the editor points out that this renders each chapter more self-sufficient. The greatest drawback of such duplication without cross-referencing is that the reader may not realise that there is a more substantial discussion of a subject elsewhere in the book. The differing choices which the two above publications have had to make, to organise the information by antigen and by organ system respectively illustrates the limitation of not using a hypermedium! Immunomicroscopy: a diagnostic tool for the surgical pathologist edited by Clive R Taylor and Richard Cote is published by Saunders Elsevier in the Major Problems in Pathology series.